Hydroxylation of zl5-Steroids with N-Bromosuccinimide to 5a,6/3-Diols
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چکیده
N-Bromosuccinimide, Zl5-Steroids, Diosgenin, Cholesterol, Stigmastane, Dehydroisoandrosterone The reaction of N-bromosuccinimide with Zl5-steroids such as, diosgenin, cholesterol, stigmasterol and dehydroisoandrosterone were studied. It was found that NBS in a solvent mixture of acetone, water and acetic acid (8:1:0.1) oxidises the olefinic bond of all the previous steroidal compounds to the corresponding «ran-sglycollic, 5a,6/?-dihydroxylic products in about 60% yield at room temperature.
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